Cell Line Lysates
Cayman Chemical 3AmIno3deoxyadenosIn5 2.5mg
An amine-modified nucleotide; has been used as a probe for quantifying ATP substrate specificity for kinases and ligases; terminates RNA strand synthesis catalyzed by RNA polymerase in E. coli
Cayman Chemical UrIdIn5O 3thIotrIphosph 2.5mg
A P2Y2 receptor agonist; induces inositol phosphate formation in 1321N1 astrocytoma cells expressing the human P2Y2 receptor (EC50 = 240 nM) and chloride secretion in primary nasal epithelial cells from patients with cystic fibrosis in a concentration-dependent manner; induces vasoconstriction in isolated human coronary arteries (EC50 = 25.1 µM)
Abcam HL-60 whole cell lysate
HL-60 whole cell lysate
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology WSTF Rabbit mAb
This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Medchemexpress LLC Keap1 protein (human, His-GST tag) | >90.0% | 10 UG
Recombinant human Keap1 protein expressed in Sf9 insect cells with N-terminal His and GST affinity tags. Supplied as a purified protein in Tris-NaCl-glycerol buffer, it is designed for biochemical and biophysical assays, protein-protein interaction studies, and antibody generation. Molecular weight is approximately 93-109 kDa and purity is reported as >90% by reducing SDS-PAGE. Store frozen and aliquot to avoid repeated freeze-thaw.
- Recombinant human protein with His and GST tags.
- Expressed in Sf9 insect cell expression system.
- Purity greater than 90% by reducing SDS-PAGE.
- Endotoxin level below 1 EU/μg.
- Supplied in 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 7.5.
- Approximate molecular weight 93-109 kDa.
- Suitable for biochemical assays and protein-protein interaction studies.
- Store at -80°C for long-term storage; stable at -20°C short term.
ABclonal Technology Bcl10 Rabbit pAb
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
ATCC HeLa S3; Cervical Adenocarcinoma; Human (Homo sapiens)
HeLa S3 cells are a clonal derivative of the parent HeLa cell line (ATCC CCL-2). The HeLa S3 clone has been very useful in the clonal analysis of mammalian cell populations relating to chromosomal variation, cell nutrition, and plaque-forming ability. This line can be adapted to grow in suspension and is a suitable transfection host. The cells are positive for keratin by immunoperoxidase staining. HeLa cells have been reported to contain human papilloma virus 18 (HPV-18) sequences.
ABclonal Technology KDM4A Rabbit mAb
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Cayman Chemical 2 3-DIdeoxyadenosIn-5-O-2.5mg
A sulfur-containing nucleoside triphosphate; prevents complete digestion by 5’-phosphodoiesterase, which allows for alkylation and identification of SNP-containing alleles when incorporated into allele-specific primers; has been used for chain extension in PCR assays; a mixture of Rp and Sp isomers
ABclonal Technology MSH6 Rabbit mAb
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.